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Christina Applegate Says She Was Misdiagnosed With MS

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What's new

New reporting adds detail that Applegate called the news 'unnerving' and 'confusing,' that she still shows MS-like symptoms, and that experts say misdiagnosis is common, with one doctor estimating up to 1 in 5 MS diagnoses may be incorrect.

This story is developing. The page was updated October 21, 2026 at 7:17 PM CDT as new reports came in.

What everyone agrees on

  • Christina Applegate said she was diagnosed with multiple sclerosis in 2021.
  • Applegate said doctors recently told her she does not have MS after all.
  • Applegate described feeling 'back at square one.'
  • Applegate has been a public advocate for MS research and awareness.

Each fact above was reported by outlets on the left, center and right.

How each side framed it

Left-leaning outlets · 7

Left-leaning outlets emphasized Applegate's advocacy history, her ongoing symptoms despite the reversed diagnosis, and included expert discussion of how misdiagnosis can happen and how many people live with rare or undiagnosed illnesses.

Center-leaning outlets · 4

Center-leaning outlets focused on how common MS misdiagnosis can be and described the diagnosis reversal after five years.

Right-leaning outlets · 1

Right-leaning coverage highlighted a doctor's statistics on how often MS diagnoses are incorrect and focused on Applegate's next steps in finding the cause of her symptoms.

Read the original reporting

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This page was written by AI from each outlet's headline and short description, following our published rules. Always check the original reporting.